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June 06.2025
3 Minutes Read

Why Educated Night Owls Face Increased Risk of Cognitive Decline

Exhausted woman at desk amid books and papers, cognitive decline risk.

Understanding Chronotypes: Early Birds vs. Night Owls

Chronotype refers to an individual's natural preference for being active during certain times of the day, often categorized as "early birds" who thrive in the morning and "night owls" who find productivity in the late hours. Chronic disruptions to these natural patterns, such as irregular sleep schedules, can have profound effects on health outcomes. Research suggests that night owls may face a higher risk of cognitive decline as they age, particularly among those with higher educational levels. This finding underscores the intersection of sleep patterns and cognitive health, prompting us to consider how lifestyle choices impact long-term mental wellbeing.

The Study: Key Findings on Cognitive Decline

A recent comprehensive study examined nearly 24,000 middle-aged and older adults in the northern Netherlands. The researchers sought to elucidate the relationship between chronotype and cognitive decline over a decade. Cognitive abilities were assessed at both the onset and conclusion of the study, focusing on non-verbal fluency and executive functions. Notably, the findings indicated a clear link: educated night owls experienced a statistically significant decline in cognitive function compared to early birds, suggesting that the tendency to stay up late could be a risk factor for dementia among this demographic.

Breaking Down the Educational Factors at Play

Interestingly, the impact of chronotype on cognitive decline was not uniform across educational backgrounds. Those with higher education levels showed a concerning trend of cognitive decline correlated with later sleep patterns. For instance, for every hour of increased lateness in sleep habits, there was a decrease of 0.80 points in cognitive assessments over ten years. This highlights the possible role that education may play in how sleep patterns affect cognitive aging.

Potential Causes: The Role of Sleep Quality

While the study established a correlation, researchers are also investigating other underlying factors that may contribute to this phenomenon. Poor sleep quality and lifestyle choices, such as smoking, can exacerbate the risks associated with a later chronotype. These factors can lead to disrupted circadian rhythms, reducing overall cognitive health. As sleep patterns increasingly align with lifestyle demands—whether due to work schedules or behavioral habits—understanding the interplay between these elements can empower individuals to modify their habits for better long-term health.

Addressing Common Misconceptions: Not All Late Sleepers are Affected Equally

One key misconception emerging from this study is that being a night owl automatically equates to an increased risk for cognitive decline. It's essential to recognize that individual health, lifestyle choices, and genetic predispositions also play critical roles. While educated night owls may have a heightened risk based on the findings, further longitudinal studies are needed to clarify these relationships and explore the protective factors that could offset these risks.

Future Predictions for Sleep Research and Cognitive Health

The implications of this study spotlight a crucial opportunity for future research: exploring personalized sleep interventions tailored to individual chronotypes. As society evolves, recognizing the nuances of personal health may lead to significant breakthroughs in mitigating cognitive decline. This could also translate into developing public health campaigns focused on promoting healthier sleep practices, particularly for those in professional settings.

Taking Action: Prioritizing Sleep for Cognitive Longevity

As awareness of the connection between sleep patterns and cognitive health grows, it becomes increasingly vital to prioritize sleep hygiene. This means establishing a consistent sleep schedule, creating a restful environment, and addressing factors that may interfere with high-quality rest. Taking proactive steps toward maintaining a balanced lifestyle can help reduce the associated risks of cognitive decline.

Conclusion: A Call to Action for a Healthier Future

With compelling evidence linking sleep patterns and cognitive health, it's crucial for individuals, particularly those in the middle-aged to senior demographics, to evaluate their sleep habits critically. Increasing attention to maintaining optimal health can pave the way for better cognitive outcomes as we age. By understanding the risks associated with being a night owl and taking proactive measures to improve sleep quality, we can foster a healthier society that prioritizes well-being and longevity.

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06.06.2025

Cataracts, Glaucoma, and AMD: Understanding Your Eye Health Options

Update Understanding Vision Issues in Older Adults As we age, our vision often deteriorates due to conditions such as cataracts, glaucoma, and age-related macular degeneration (AMD). June is recognized as Cataract Awareness Month, making it an opportune moment to delve into these prevalent eye issues that greatly affect older adults. With advancements in eye care technology and surgical techniques, many can now preserve their eyesight effectively. What are Cataracts and How are They Treated? Cataracts form when the eye's natural lens becomes cloudy, leading to blurred vision, especially at night. According to the CDC, over 20 million Americans aged 40 and older are affected by cataracts. Thankfully, treatment options have evolved over the years. Cataract surgery, a procedure in which the cloudy lens is removed and replaced with an intraocular lens (IOL), has been performed on more than 6 million Americans annually. Advancements in implant technology have introduced several lens options, including toric lenses to correct astigmatism and multifocal lenses allowing patients to focus on objects at different distances. Dr. Michelle Andreoli, an ophthalmologist at Northwestern Medicine, emphasizes that while the core surgical techniques have remained stable for decades, the customization available today greatly enhances patient outcomes. The Silent Threat of Glaucoma Often dubbed the 'silent thief of sight,' glaucoma is characterized by excessive eye pressure that can cause irreversible damage to the optic nerve. With an estimated 4.2 million Americans suffering from this condition, regular eye exams are crucial for early detection. Treatment can include eye drops to lower intraocular pressure, laser surgery, or a combination of both. One innovative approach gaining traction is minimally invasive glaucoma surgery (MIGS), which allows surgeons to address both cataracts and glaucoma simultaneously through a single incision. This dual treatment option not only alleviates symptoms but may also help patients reduce their reliance on medication. The shift from a lifelong dependency on eye drops to a focus on improving patients' quality of life is a testament to the evolving landscape of glaucoma care. Age-Related Macular Degeneration: Risks and Treatments AMD leads to a gradual loss of central vision and impacts nearly 20 million Americans, making it one of the most common causes of vision loss in older adults. The condition typically progresses from dry AMD—characterized by thinning of the macula and formation of tiny protein clumps—to wet AMD, marked by the growth of abnormal blood vessels that can leak and scar the retina. While there’s no cure, various treatments can slow the progression. For dry AMD, it is essential to undergo regular eye examinations and consider nutritional supplementation as recommended by the National Eye Institute. In cases of wet AMD, injections targeting the unhealthy blood vessels are standard practice and can significantly reduce vision deterioration. Maintaining Vision Health: Preventive Measures and Awareness Awareness and proactive management of eye health are key to minimizing the impact of aging-related vision disorders. Staying informed about the symptoms and being proactive in scheduling eye exams can make all the difference. Moreover, integrating eye-healthy practices such as a balanced diet rich in antioxidants, regular physical activity, and smoking cessation can contribute to long-term ocular health. Embracing these strategies not only protects your eyesight but also improves overall health and quality of life. In conclusion, understanding the risks associated with cataracts, glaucoma, and AMD, coupled with advancements in treatment, empowers older adults to take charge of their vision health. Regular check-ups and awareness can lead to timely interventions and better outcomes. Don’t wait to schedule your eye exam—your vision deserves it.

06.04.2025

Can Targeting Inflammation Slow Alzheimer’s Progression in Mice?

Update Can Targeting Inflammation Slow Alzheimer’s Progression in Mice? Recent breakthroughs in Alzheimer’s research reveal promising strategies that may not only enhance cognitive function in affected models but also provide insights for future therapeutic approaches towards neurodegenerative diseases. Understanding Inflammation’s Role in Alzheimer’s Alzheimer’s disease is marked by the complex interaction of various pathological features, primarily the accumulation of amyloid beta (Aβ) plaques and tau tangles in neuronal tissues. Studies suggest that inflammation significantly exacerbates these conditions, driving the pathogenic process beyond mere plaque accumulation. The chronic stress imposed on neurons by these accumulations initiates a cascade of cellular responses, particularly within the brain's immune cells known as microglia. When activated, these cells can shift from a protective role to an aggressively inflammatory one, further damaging surrounding neurons. This underpins the necessity of exploring new therapeutic targets, focusing on inflammatory pathways such as the cGAS-STING pathway. A Closer Look at the cGAS-STING Pathway The cGAS-STING pathway is a DNA-sensing mechanism that becomes activated in response to cytoplasmic DNA—often resulting from cellular stress. In the context of Alzheimer’s, this pathway's activation is believed to worsen inflammation and neuronal damage, thereby contributing to cognitive decline. By inhibiting this pathway, researchers propose a dual benefit: reducing inflammation while also mitigating amyloid accumulation—each pivotal in the progression of Alzheimer’s. This was precisely the focus of a study conducted by the University of Virginia, which employed a genetic approach to confirm the role of STING in Alzheimer’s pathology. Key Findings from Recent Research In this groundbreaking study, scientists crossed a model known for early amyloid deposition (5xFAD) with STING gene-deficient mice and observed remarkable outcomes. Mice lacking the STING pathway demonstrated not only improved cognitive performance on maze tests but also a significant reduction in levels of harmful Aβ42—a major contributor to Alzheimer’s pathology. Furthermore, histological examinations indicated reduced plaque burden and a less aggressive microglial phenotype. These milder immune responses likely contribute to the observed cognitive benefits, heralding an exciting prospect for future Alzheimer's therapies. Potential Impact on Future Alzheimer's Treatments This innovative approach lays the groundwork for a new class of Alzheimer’s treatments that address the inflammatory components of the disease. By fostering a calmer microglial response, therapies targeting the cGAS-STING pathway could emerge as valuable options, potentially reshaping how we think about treating cognitive decline. Moreover, the implications of this research stretch beyond Alzheimer’s alone, suggesting that similar mechanisms may operate in other neurodegenerative conditions. The challenge now lies in translating these findings from animal models to human applications—a significant and complex journey ahead. Challenges and Future Research Directions While the results from the University of Virginia provide hope, researchers must navigate various challenges to optimize these findings for clinical use. One prominent issue is the distinction between results observed in female mice and their generalizability across genders. Additionally, studies must explore the potential long-term effects of inhibiting the STING pathway in broader, more diverse populations. As researchers develop and refine protocols for targeting inflammation in neurodegenerative diseases, ongoing investigations will be crucial in understanding the full scope of implications and the practicalities of clinical applications. Conclusion: The Road Ahead The research highlighting the role of the cGAS-STING pathway not only illuminates a novel therapeutic avenue for Alzheimer’s treatment but also emphasizes the importance of understanding immune dynamics in neurodegeneration. As scientists continue to untangle the complexities of Alzheimer’s disease, approaches like these offer a glimmer of hope for those affected by cognitive decline.

06.04.2025

Granfluencers: Redefining Aging and Health Through Social Media Influence

Update Understanding the Rise of GranfluencersAs the landscape of social media continues to evolve, a new and vibrant demographic is emerging: the Granfluencers. These individuals—typically defined as older adults who possess a strong online presence—are leveraging platforms to share their stories, experiences, and insights. But what does this mean for both the aging population and society at large?Portrait of Granfluencers: A Generation Like No OtherGranfluencers differ significantly from traditional influencers. They embody authenticity and relatability, often attracting followers through genuine engagement rather than curated perfection. While conventional social media stars might emphasize aesthetics and trends, Granfluencers focus on real-life experiences and valuable advice, particularly in niches like health, wellness, and lifestyle. Their candid nature fosters a sense of community among followers who resonate with their journeys.Why Granfluencers Matter: A Cultural ShiftThe relevance of Granfluencers extends beyond their personal narratives. Their increasing visibility challenges societal norms surrounding aging and shapes perceptions of older adults in media. Typically, media portrayal of aging has leaned toward stereotypes—individuals depicted as frail or disconnected. Granfluencers break this mold, illustrating that age doesn’t equate to obsolescence. Instead, they represent wisdom, resilience, and the potential for reinvention at any stage of life.The Benefits of Granfluencers on Health and LongevityResearch consistently underscores the health advantages of social connections, particularly for older individuals. Granfluencers serve as accessible models for healthy living, promoting practices such as fitness routines, nutritional advice, and mental wellness strategies. Their influence encourages their followers to prioritize their health actively while creating a supportive environment among their online communities. As they share successes and challenges, they offer realistic portrayals of aging that can motivate others to adopt healthier lifestyles.Bridging the Gap: Understanding Granfluencer Impact on Younger GenerationsGranfluencers are more than just role models for older adults; they have much to offer younger generations as well. The intergenerational dialogue facilitated by these influencers can bridge gaps of understanding between age groups, paving the way for increased empathy and cooperation. Younger individuals benefit from the wisdom of their elders while gaining insights into effective strategies for self-care and resilience—lessons often overshadowed in typical youth-oriented media.Future Insights: Granfluencers and the Evolving Social Media LandscapeThe future promises further expansion of the Granfluencer movement, particularly as the aging population continues to increase. Brands and organizations will likely recognize the potential of harnessing this demographic for authentic marketing and community-building efforts. As such, Granfluencers may find opportunities to collaborate with companies that share their values. We may soon see an entirely new genre of brand partnerships that celebrate authenticity and the importance of health at every age.The Call to Action: Engaging with GranfluencersWhether you’re a young adult seeking inspiration or an older individual looking for camaraderie, consider tapping into the Granfluencer community. Manufacturer support for their campaigns can enhance visibility and foster valuable discussions around health and well-being. Seek out these voices in the digital space and engage with their content. Remember, their stories not only celebrate aging but also enrich our understanding of life at all stages.

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Lake","state":"MI","zip":"49456","email":"group@aimarketingshift.com","tos":"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","privacy":"PHA+PHN0cm9uZz5QUklWQUNZPC9zdHJvbmc+PC9wPgoKPHA+PHN0cm9uZz5UaGUgaW5mb3JtYXRpb24gcHJvdmlkZWQgZHVyaW5nIHRoaXMgcmVnaXN0cmF0aW9uIGlzIGtlcHQgcHJpdmF0ZSBhbmQgY29uZmlkZW50aWFsLCBhbmQgd2lsbCBuZXZlciBiZSBkaXN0cmlidXRlZCwgY29waWVkLCBzb2xkLCB0cmFkZWQgb3IgcG9zdGVkIGluIGFueSB3YXksIHNoYXBlIG9yIGZvcm0uIFRoaXMgaXMgb3VyIGd1YXJhbnRlZS48L3N0cm9uZz48L3A+Cgo8cD48c3Ryb25nPklOREVNTklUWTwvc3Ryb25nPjwvcD4KCjxwPjxlbT5Zb3UgYWdyZWUgdG8gaW5kZW1uaWZ5IGFuZCBob2xkIHVzLCBhbmQgaXRzIHN1YnNpZGlhcmllcywgYWZmaWxpYXRlcywgb2ZmaWNlcnMsIGFnZW50cywgY28tYnJhbmRlcnMgb3Igb3RoZXIgcGFydG5lcnMsIGFuZCBlbXBsb3llZXMsIGhhcm1sZXNzIGZyb20gYW55IGNsYWltIG9yIGRlbWFuZCwgaW5jbHVkaW5nIHJlYXNvbmFibGUgYXR0b3JuZXlzJiMzOTsgZmVlcywgbWFkZSBieSBhbnkgdGhpcmQgcGFydHkgZH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